Acid-Catalyzed ortho-Alkylation of Anilines with Styrenes: An Improved Route to Chiral Anilines with Bulky Substituents.
نویسندگان
چکیده
منابع مشابه
Copper-catalyzed ortho-halogenation of protected anilines.
A practical Cu-catalyzed direct ortho-halogenation of anilines under aerobic conditions has been developed. The reaction shows typically excellent mono-substitution selectivity, high ortho-regiocontrol and large functional group tolerance.
متن کاملRoom temperature and solvent-free iridium-catalyzed selective alkylation of anilines with alcohols.
A bidentate iridium NHC-phosphine complex has been developed and applied to the N-monoalkylation of aromatic amines with a wide range of primary alcohols and to the N-heterocyclization of amino alcohols. This reaction resulted in high isolated product yields, even at room temperature and under solvent-free conditions.
متن کاملIron(II)-catalyzed enantioselective meso-epoxide-opening with anilines.
A highly enantioselective method for the catalytic opening of aromatic meso-epoxides with aniline derivatives was developed. The desired chiral β-amino alcohols were obtained in mostly good to very good yields with excellent enantioselectivities. Structural evidence of the pre-catalyst revealed a scarcely disclosed heptadentate Fe(II) complex with the chiral bipyridine ligand.
متن کاملAnilines Oxidation with Chlorine Dioxide in Wastewater
Oxidative behaviors of three toxic pollutants including aniline, p-toludine and p-chloroaniline with ClO2 in water were studied with HPLC. The removal rates of anilines were used as criteria in this experiment. Effects of the ClO 2 concentration, pH and reaction time on the removal rate of anilines were discussed. The results show that for 1mmol ·L-1 aniline, p-toludine and p-chloroaniline, the...
متن کاملPara-selective gold-catalyzed direct alkynylation of anilines.
A method for the para-selective alkynylation of anilines is reported using AuCl as catalyst and triisopropylsilylethynyl-1,2-benziodoxol-3(1H)-one (TIPS-EBX) as an electrophilic acetylene equivalent. Para-alkynyl anilines substituted at positions 2 or 3 were obtained in one step from simple anilines under mild conditions (room temperature to 60 °C) under air. The methodology could also be exten...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ChemInform
سال: 2006
ISSN: 0931-7597,1522-2667
DOI: 10.1002/chin.200612101